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Codon-level information improves predictions of inter-residue contacts...

Codon-level information improves predictions of inter-residue contacts... Methods for analysing correlated mutations in proteins are becoming an increasingly powerful tool for predicting contacts within and between proteins. Nevertheless, limitations remain due to the requirement for large multiple sequence alignments (MSA) and the fact that, in general, only the relatively small number of top-ranking predictions are reliable.

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