פוטוניקה

BINA scientists are developing a technique for measuring the local spectrum at each point of a sample. The spectrum contains much more information than just a color image, and can be used for diagnostics and other biomedical applications. The team aims for fast measurements of a large sample under a microscope, so that a pathological sample can be diagnosed in a rather rapid manner. These measurements are based on Fourier spectroscopy, which relies on collecting the light from the sample through a unique optical system.

The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissues’ optical parameters. Intraoperative detection of residual disease in oral cancer may reduce the high rate of recurrences. The aim of this study was to check the sensitivity of the DR measurement of Gold Nanoparticles (GNP) in a rat model of oral squamous cell carcinoma. The results of the present study clearly demonstrate the power of the direct DR scanning in identifying carcinomatous changes in tissue sections. The direct DR scanning can be used as a simple tool for detecting residual disease intraoperatively.

Monitoring the dynamics of droplet evaporation has diverse potential applications, such as characterizing the surface and combustion efficiency of fuels. A BINA team has developed a technique for the monitoring of the evaporation of sub nano-liter volume droplets. The method is based on the dynamically-varying interaction between the fluid, the surface to which it is applied and its surroundings. In this method, the interference fringes of reflections from a pendent droplet at the tip of a standard fiber are recorded and analyzed. The temporal profiles obtained in the experiments provide distinct signatures of the specific fluids.