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Bioconvergence

Bioconvergence

 

Researchers

  • The Biofilm Research Laboratory

    TEM micrographs of S. aureus (cyan) treated with the synthesized nano-particles (yellow). The nano particles target bacteria and mark them for destruction.

    • Bacterial biofilms
    • Nanoparticles with anti-biofilm properties
    • Bacterial virulence
    • Bio-ethanol production

  • Computational Systems Immunology

    An example of a project workflow in our lab, from sample collection to antigen binding and health status prediction.

    • Computational
    • immunology Systems biology
    • Machine Learning

  • Neuroengineering and Regeneration

    The image shows florescent NPs injected into cells in the leech CNS ganglion via an electrode (shown near the orange injected neuron).

    • Neurobiological systems development: image processing and network analysis
    • Tissue Engineering: Developing skin grafts that enable reinnervation and regeneration
    • Developing devices for reagents delivery into live tissue at a microscopic resolution
    • Neuroprosthetic devices: Neuron-Chip interface

  • Nanotheranostics for Personalized Medicine

    Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma

    • Molecular CT imaging of cancer using targeted gold nanoparticles.
    • Theranostic approaches for Alzheimer’s and Parkinson’s Diseases.
    • Metabolic based imaging and therapy.
    • Optical/chamical imaging of enzymatic activity.
    • Nanoparticle-based strategies for targeted drug delivery.
    • In-vivo cell tracking techniques.

  • Mechanism and machinery of nucleolar gene silencing

    • The use of nanoparticles for cytoplasmic and nuclear gene silencing
    • Trans-splicing in trypanosomatids
    • Protein translocation in trypanosomatids
    • RNA modifications mediated by guide RNAs
    • RNAi silencing in plants
    • The use of nano particles as RNAi carriers into the nucleous

  • Ophthalmic Science and Engineering Lab

    Retinal implant with photoreceptor precursors integrated within microwells.

    • Electro-cellular interfaces, optical and electronic micro-devices development
    • Applied science for improving diagnosis, treatment and prevention of various ophthalmicdiseases.
    • Artificial introduction of the visual information and its processing by the retina and the visual cortex.
    • Electro-cellular interface with the autonomic system and application of high electrical field for solid tumor ablation (IRE - Irreversible Electroporation).