Bioconvergence is a new interdisciplinary scientific research area that combines biotechnology, chemistry, engineering, and computer science to solve complex challenges in healthcare, sustainability, agriculture, and other fields. It enables innovations such as personalized medicine, regenerative therapies, advanced diagnostics, and bio-inspired materials. Bioconvergence has the potential to transform the way we prevent, predict, and treat diseases, as well as improve the quality of life for millions of people around the world. Researchers at BINA are involved in various aspects related to bioconvergence, including:

  • Biochips
  • Biosensors
  • Human Organs-on-chips
  • Neuron-chip and cell-chip interfaces
  • Optical and electronic micro-devices
  • Microfluidics and Lab on chip
  • Electrochemical sensors


  • Prof. Ehud Banin

    BINA Director

    Prof. Ehud Banin

    BINA Director

    The Biofilm Research Laboratory

    TEM micrographs of S. aureus (cyan) treated with the synthesized nano-particles (yellow). The nano particles target bacteria and mark them for destruction.

    • Bacterial biofilms
    • Nanoparticles with anti-biofilm properties
    • Bacterial virulence
    • Bio-ethanol production

  • Optical Imaging and Biosensing Laboratory


    Improving the Sensitivity of Fluorescence-based Immunoassays by Photobleaching the Autofluorescence of Magnetic Beads

    • Rapid and highly sensitive detection of biomarkers, such as proteins and specific DNA sequences
    • Detection of protein-protein interactions
    • Magnetic manipulation of nanoparticles, design of magnetic poles, magnetic force optimization

  • Nano photonics, Fluorescence Imaging and Microscopy Research

    Identification of macrophages cells with gold nanorods

    • Fluorescence lifetime and anisotropy decay
    • Fluorescence lifetime imaging (FLIM)
    • Biological imaging based on fluorescence parameters
    • Super resolution
    • Light-tissue interaction

  • Protein-DNA interactions and proteinbased materials

    Our work focuses on designing proteins for protein-based materials and to explore protein-DNA interactions

    The Golub lab aims to elucidate the mechanisms that govern various aspects of nanobiotechnology and harness them to generate the next-generation of biomaterials. On the one hand, we focus on elucidating the various mechanisms that govern non-canonical DNA-protein interactions at important biological crossroads from a biophysical perspective. Derived insights could serve in the future as a solid foundation for the development of highly selective and specific ligands, both for therapeutic purposes as well as for the development of sensitive biosensors. Additionally, methods for the preparation of novel protein-based nanobiomaterials and nanoreactors are being devised based on revolutionary protein building blocks. Such materials aim to harness the structural diversity and precision that can be found in proteins with the nanosized effects that stem from nanostructures.

  • Sex Determination

    Sex Determination

    • 3D Genome organisation
    • CRISPR genome editing
    • Stem Cell Biology
    • Developing in vitro systems to model the gonads

  • Precise and efficient CRISPR genome editing as a curative therapy for genetic disorders



    • Biotechnology
    • Genetic therapy
    • Genetic engineering
    • Developing CRISPR technology as a method of gene therapy for genetic diseases

  • Sensitive magnetic imaging

     Sensitive magnetic imaging reveals stripy current flow at the interface between two oxides, which is related to the structure of strontium titanate.

    • Superconductivity
    • Nano-magnetism
    • Bio-magnetism
    • Scanning SQUID microscopy
    • Complex oxid interfaces
    • Nano-electronics

  • Single-cell genomics of kidney development, regeneration, and cancer


    2D embedding of single cell gene expression profiles in the developing embryonic kidney

    • Biochips & Sensors
    • Disease Treatment
    • Drug Delivery
    • Genomics, Proteomics & Glycomics
    • Imaging

  • Ophthalmic Science and Engineering Lab

    Retinal implant with photoreceptor precursors integrated within microwells.

    • Electro-cellular interfaces, optical and electronic micro-devices development
    • Applied science for improving diagnosis, treatment and prevention of various ophthalmicdiseases.
    • Artificial introduction of the visual information and its processing by the retina and the visual cortex.
    • Electro-cellular interface with the autonomic system and application of high electrical field for solid tumor ablation (IRE - Irreversible Electroporation).

  • Mechanism and machinery of nucleolar gene silencing

    • The use of nanoparticles for cytoplasmic and nuclear gene silencing
    • Trans-splicing in trypanosomatids
    • Protein translocation in trypanosomatids
    • RNA modifications mediated by guide RNAs
    • RNAi silencing in plants
    • The use of nano particles as RNAi carriers into the nucleous

  • Optical and Acoustical Neuroimaging Lab

    Optical and Acoustical Neuroimaging Lab

    Our neuroengineering research focuses on developing advanced acoustical and optical neuroimaging methods to understand the brain's neural circuitry and fundamental mechanisms. These methods have significant potential in brain-computer interfaces and clinical studies. We combine cutting-edge Electrical Engineering and Neuroimaging techniques, including single photon sensing, superconductive sensing, machine learning, FPGA design, nanoelectronics, biomedical sensing, and neuroimaging.

  • Nanotheranostics for Personalized Medicine

    Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma

    • Molecular CT imaging of cancer using targeted gold nanoparticles.
    • Theranostic approaches for Alzheimer’s and Parkinson’s Diseases.
    • Metabolic based imaging and therapy.
    • Optical/chamical imaging of enzymatic activity.
    • Nanoparticle-based strategies for targeted drug delivery.
    • In-vivo cell tracking techniques.

  • Light-matter interaction at the nanoscale


    Large-scale nonporous metallic network is belong to a unique class of light materials with photocatalytic and optical properties which we develop in my lab.

    The overall goal of my laboratory is to develop, fabricate and to use plasmonic systems as a ‘photonic environment’, or even as a ‘photonic catalyst’. In general, we aim at opening new routes for photochemical processes/reactions on surfaces by controlling the electromagnetic-field properties at the metal surface, that is, to do, 'chemistry with plasmons'.

  • Phase transitions on the nano-scale

    • Spintronics
    • New Temperature Coefficient of Resistance (TCR) materials
    • Organic/SC hybrid
  • Neuroengineering and Regeneration

    The image shows florescent NPs injected into cells in the leech CNS ganglion via an electrode (shown near the orange injected neuron).

    • Neurobiological systems development: image processing and network analysis
    • Tissue Engineering: Developing skin grafts that enable reinnervation and regeneration
    • Developing devices for reagents delivery into live tissue at a microscopic resolution
    • Neuroprosthetic devices: Neuron-Chip interface

  • In the Device Spectroscopy Laboratory, we use optical spectroscopy to study nanoscale materials such as molecular organics and more generally nanostructured semiconductors, and then devices composed of these materials

     Monolayer VCSEL laser formed from dielectric mirrors with a monolayer of fluorescence dye molecules sitatued between them providing optical gain

    • Coherent coupling in light-matter coupled systems: Organic Lasers, J-aggregates, and Polaritons.

    • Ultra-high resolution scanning microcopy and spectroscopy.
    • Applications of ultra-fast non-linear spectroscopy for energy sustainability.
    • Novel approaches to organic crystal growth and OLED deposition

  • Computational Systems Immunology

    An example of a project workflow in our lab, from sample collection to antigen binding and health status prediction.

    • Computational
    • immunology Systems biology
    • Machine Learning

  • Bioengineering and Regenerative Medicine

    Bioengineering and Regenerative Medicine

    A single cardiomyocyte, micropatterned on soft silicon surface. The images demostrates two views of uptake of fluorescently labeled extracellular vesicles in the cardiomyocyte.

    Image was taken by a spinning disk Olympus microscope.