Inside a single edited cell
What happens inside a single edited cell matters - and now we can finally see it.
In an innovative new study, Prof. Ayal Hendel, Nechama Kalter, and Dr. Michael Rosenberg, in collaboration with Mission Bio team (CA, USA), used single-cell DNA sequencing to map CRISPR editing outcomes in stunning detail. They tracked which edits happened in which cells, detected rare off-target events, and even linked genetic changes to protein expression - all in one assay.
This level of resolution is a major step forward for gene and cell therapies. It brings us closer to treatments that aren't just powerful, but also safe, consistent, and truly personalized.
It’s not just about making edits anymore. It’s about understanding their full impact - cell by cell.
Huge congrats to Prof. Hendel and everyone involved in this work.
